Metastasis of malignant melanoma
Friday 26 February 2010, Jozef Baláž, M. D.
Metastasis of malignant melanoma to the stomach:
- malignant melanoma of GI tract can be also primary
- GI metastases of malignant melanoma are common
- metastases into small bowel are more common than esophageal, stomach and large bowel metastases
- usually polypoid ulcerated lesions, very often multiple, either pigmented or non pigmented
- symptoms similar to other GI tumors
- high index of suspicion for GI malignant melanoma metastases in patients with GI symptomps and history of malignant melanoma (metastases may present also decades after the diagnosis of primary tumor)
- diagnosis: CT, endoscopy, PET + specific immunohistochemistry studies of biopsy specimens (HMB-45, S100)
