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Dieulafoy lesion

Thursday 10 July 2008, Branislav Kunčak, M. D. and Rudolf Králik, M.D.

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Dieulafoy lesion

  • is a vascular abnormality, that can be a cause of massive gastrointestinal bleeding
  • first described by French surgeon Dieulafoy in 1898 as exulceratio simplex
  • the bleeding lesion is an abnormally large, superficial localized (in the muscularis mucosa) eroded artery which is not associated with inflammation or atherosclerosis
  • the etiology is not known
  • it is usually localized in the cardia or upper part of the stomach
  • diagnosis of the lesion is based on endoscopic criteria: 1. active spurting or oozing bleeding from a minute (less than 3mm) mucosal defect or from normal surrounding mucosa 2. protruding vessel within a minute mucosal defect or normal surrounding mucosa 3. adherent clot with a narrow point of normal-appearing mucosa
  • endoscopic therapies are now the first option in the management of Dieulafoy´s lesion
  • mechanical endoscopic therapies (hemoclipping and endoscopic band ligation) appears to be more succesful than epinephrine injection in achieving permanent hemostasis

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Bigger image Endoscopy

Fig. 1

Arterial bleeding from Dieulafoy´s lesion in the subcardial region of gastric body.

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Fig. 2

Hemoclip is applying on the bleeding vessel.

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Fig. 3

Haemostasis was achieved by placement of 3 clips.

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Fig. 4

24 hours after the episode of bleeding.

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Fig. 5

Dieulafoy lesion (protriding vessel within a minute mucosal defect) along the lesser curve in the upper part of gastric body. Finding in a patient examined for acute upper GI bleeding.

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Fig. 6

Injection of epinephrine.

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Fig. 7

Hemoclipping.

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Fig. 8

Several days after hemoclipping.

Keywords: Dieulafoy lesion, exulceratio simplex, vascular abnormality, gastrointestinal bleeding, endoscopic therapy, mechanical endoscopic therapies, haemoclips, hemiclipping, endoscopic band ligation